Carboxylic acids and derivatives
Chemscene ChemScene | Tetraxetan | 5G | CS-0046228 | 0.97 | 60239-18-1| MFCD00068657 | 404.42
ChemScene | Tetraxetan | 5G | CS-0046228 | 0.97 | 60239-18-1| MFCD00068657 | 404.42
Medchemexpress LLC Iacs-8803 diammonium | 00-00-0 | 98.8% | 726.60 g/mol | C20H29FN12O9P2S2 | 5 MG
IACS-8803 diammonium is a potent cyclic dinucleotide STING agonist for preclinical research that activates the STING pathway and has demonstrated systemic antitumor efficacy. The diammonium salt form improves stability for handling and experimental use and is supplied with supporting analytical and safety documentation for research workflows.
- High purity suitable for research use (98.8%).
- Potent STING agonist activity for immuno-oncology studies.
- Suitable for both in vitro and in vivo preclinical experiments.
- Provided with SDS, COA, HNMR, LCMS, and analytical reports.
- Available in multiple small research pack sizes for dose-ranging studies.
Sigma Aldrich Fine Chemicals Biosciences Sodium Citrate Tribasic Dihydrate | 6132-04-3 | MFCD00150031 | 100g
Sodium Citrate Tribasic Dihydrate | Purity: 99% | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 100g
Medchemexpress LLC Fmoc-NH-PEG1-CH2COOH | 260367-12-2 | 99.5% | 341.36 g/mol | C19H19NO5 | 1 G
Fmoc-NH-PEG1-CH2COOH is an Fmoc-protected PEG-based linker with a terminal carboxylic acid, designed for installation of linkers in medicinal chemistry workflows such as ADC and PROTAC synthesis.
- Used in antibody-drug conjugate linker synthesis.
- Used in proteolysis-targeting chimera (PROTAC) synthesis.
- Contains an Fmoc-protected amine and a terminal carboxylic acid for conjugation.
- White to off-white solid with good purity for research applications.
- Available in multiple sizes, including 1 g, for flexible laboratory use.
Medchemexpress LLC 5,8,11,14,17,20-hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | 99.4% | 561.62 | C29H39NO10 | 250 MG
Fmoc-NH-PEG6-CH2COOH is an Fmoc-protected polyethylene glycol (PEG6) linker with a terminal carboxylic acid, supplied for research use as a cleavable linker for antibody-drug conjugates and as a PEG-based PROTAC linker in targeted protein degradation research.
- Fmoc-protected amine with terminal carboxylic acid functionality.
- Suitable for ADC and PROTAC linker synthesis.
- Reported purity 99.4% and molecular weight 561.62.
- Molecular formula C29H39NO10.
- Available in small-scale pack sizes including 250 MG.
Medchemexpress LLC Mosapride citrate | 112885-42-4 | 99.96% | 5 MG
Mosapride citrate is an orally active gastroenterokinetic compound, acting as a 5HT4 agonist and a CYP inducer. It demonstrates a concentration-dependent inhibitory effect on Kv4.3 with an IC50 value of 15.2 μM. This compound is suitable for use in the study of gastrointestinal diseases.
- Acts as a 5HT4 agonist
- Functions as a CYP inducer
- Exhibits concentration-dependent inhibitory effect on Kv4.3 with an IC50 of 15.2 μM
- Promotes gastric emptying
- Relieves NSAID-induced ulcers by activating the 5-HT4 receptor
Medchemexpress LLC Fmoc-NH-PEG6-CH2COOH | 437655-96-4 | 99.4% | 5 G
Fmoc-NH-PEG6-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This compound leverages the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Cleavable ADC linker
- PEG-based PROTAC linker
- Utilized in antibody-drug conjugate (ADC) synthesis
- Used in PROTAC synthesis
- Leverages intracellular ubiquitin-proteasome system
Medchemexpress LLC HO-PEG-CH2COOH | 10000 | HO-(CH2CH2O)n-CH2COOH | 500 MG
HO-PEG-CH2COOH (MW 10,000) is a polyethylene glycol (PEG) polymer terminated with a hydroxyl group and a terminal carboxylic acid. The manufacturer describes it as suitable for use as a PROTAC linker in the synthesis of PROTAC molecules and supplies product documentation including a data sheet and SDS.
Medchemexpress LLC Cyclic GMP-AMP diammonium | 96.6% | 708.47 g/mol | C20H30N12O13P2 | 5 MG
cGAMP diammonium is a cyclic dinucleotide that functions as an endogenous second messenger and a potent activator of the stimulator of interferon genes (STING) pathway. Provided as the diammonium salt for research use, it induces type I interferon production and is used to study innate immune signaling.
- Activates STING and triggers type I interferon signaling.
- High purity (96.6%) suitable for research applications.
- Molecular formula C20H30N12O13P2; molecular weight 708.47 g/mol.
- Water-soluble; dissolves up to 100 mg/mL with ultrasonic assistance.
- Solid storage recommended at -20°C; solution storage guidance provided.
- Supplied in small quantities (e.g., 5 mg) for laboratory use.
Medchemexpress LLC Boc-NH-PEG1-CH2COOH | 142929-49-5 | 98.0% | C9H17NO5 | 1 G
Boc-NH-PEG1-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Molecular weight: 219.23
- Appearance: Solid-liquid mixture
- Color: Colorless to light yellow
- SMILES: O=C(O)COCCNC(OC(C)(C)C)=O
- Storage (pure form): -20°C for 3 years, 4°C for 2 years
- Storage (in solvent): -80°C for 6 months, -20°C for 1 month
- Solubility (in vitro): DMSO at 100 mg/mL (456.14 mM)
- Solubility (in vivo): Protocols available for DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil
eMolecules 29949-81-3 | Tris(4-bromophenyl)phosphane | MFCD02690473 | 250mg
Ambeed | (S)-2-Amino-3-(7-chloro-1H-indol-3-yl)propanoic acid | 100mg | 525092784 | A175659 | 73945-46-7 | MFCD09264322 | 238.670 | C11H11ClN2O2
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Teknova 20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
20mM Sodium Citrate, 8% Sucrose, pH 6.0. 500mL, Endotoxin Tested, Sterile. 8 pack.
Sigma Aldrich Fine Chemicals Biosciences Sodium citrate tribasic dihydrate BioUltra, for molecular biology | 6132-04-3 | MFCD00150031 | 100G
Sodium citrate tribasic dihydrate BioUltra, for molecular biology | Mol Wt: 294.1 | 6132-04-3 | MFCD00150031 | 100G
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | >=97.0% | 100 MG
Bromo-PEG1-CH2COOH is a PROTAC linker, designed for use in the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, by connecting an E3 ubiquitin ligase ligand to a target protein ligand.
- Used as a PROTAC linker
- Designed for PROTAC synthesis
- Contains two ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a protein
- Exploits the ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Medchemexpress LLC SPD-473 citrate | 161190-26-7 | MFCD31382144 | 99.8% | 552.47 g/mol | C23H31Cl2NO8S | 1 MG
SPD-473 citrate is the citrate salt of a triple reuptake inhibitor that blocks serotonin, dopamine, and norepinephrine transporters. Supplied for research use, it is a characterized white to off-white solid with documented purity and solubility data for in vitro and in vivo studies.
- Acts as a serotonin, dopamine, and norepinephrine reuptake inhibitor.
- High purity (99.8%).
- Molecular weight 552.47 g/mol.
- White to off-white solid suitable for laboratory handling.
- High solubility in DMSO (100 mg/mL); in vivo formulation protocols provided.
- Available in 1 mg, 5 mg, 10 mg, and 25 mg pack sizes for screening and pilot studies.